Longitudinal Relaxation Effects of Water at Ultra-High Field Strengths
My doctoral student, Patrick Sloan, is looking at errors in longitudinal relaxation time (T1) due to radiation damping at ultra-high field strengths. In nuclear magnetic resonance experiments this error is reduced by "detuning" or minimizing water signal by using deuterated water as solvent. However such techniques are impractical in vivo where accurate longitudinal relaxation times are necessary for predictable image weighting and quantitative imaging experiments. As such he is assessing the effect of water (proton) concentration as a function of field strength to see if a predictable correction is possible.